Primary Identifier | MGI:95492 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 14121 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables fructose 1,6-bisphosphate 1-phosphatase activity. Involved in gluconeogenesis. Predicted to be located in extracellular space and nucleus. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; cerebral cortex; facial bone primordium; ganglia; and genitourinary system. Human ortholog(s) of this gene implicated in fructose-1,6-bisphosphatase deficiency. Orthologous to human FBP1 (fructose-bisphosphatase 1). PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit reduced fasting glucose levels. [provided by MGI curators] |