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Protein Coding Gene : Fbp1 fructose bisphosphatase 1

Primary Identifier  MGI:95492 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  14121
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables fructose 1,6-bisphosphate 1-phosphatase activity. Involved in gluconeogenesis. Predicted to be located in extracellular space and nucleus. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; facial bone primordium; ganglia; genitourinary system; and liver. Human ortholog(s) of this gene implicated in fructose-1,6-bisphosphatase deficiency. Orthologous to human FBP1 (fructose-bisphosphatase 1).
PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit reduced fasting glucose levels. [provided by MGI curators]
  • synonyms:
  • Fbp3,
  • FBPase brain isoform,
  • MGI:1330236,
  • fructose bisphosphatase 3,
  • MGD-MRK-9722,
  • fructose bisphosphatase 1,
  • MGD-MRK-9720,
  • FBPase liver,
  • fructose bisphosphatase 2,
  • Fbp-2,
  • Fbp1

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For