Primary Identifier | MGI:1891713 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 56541 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including SUMO binding activity; hyaluronic acid binding activity; and translation elongation factor binding activity. Predicted to be involved in PML body organization; cellular response to mechanical stimulus; and regulation of gene expression. Predicted to act upstream of or within hyaluronan metabolic process. Located in cytoplasm. Is active in synapse. Is expressed in central nervous system; ovary; retina; and white fat. Orthologous to human HABP4 (hyaluronan binding protein 4). PHENOTYPE: Mice homozygous for a null allele exhibit increased proliferation of cells in the bottom of the colon crypts and show increased colon tumor development following chemical induction. [provided by MGI curators] |