Primary Identifier | MGI:2145528 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 97895 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable molecular adaptor activity. Involved in several processes, including actin filament organization; in utero embryonic development; and positive regulation of embryonic development. Located in cell cortex. Is expressed in several structures, including early conceptus; genitourinary system; hemolymphoid system gland; liver; and muscle tissue. Orthologous to human NLRP4 (NLR family pyrin domain containing 4). PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced female fertility, a maternal effect on preimplantation embryo development, altered organelle distribution in zygotes and oocytes, and abnormal formation of microtubules and cytoplasmic lattices in oocytes. [provided by MGI curators] |