| Primary Identifier | MGI:98400 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 78925 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables 3-oxo-5-alpha-steroid 4-dehydrogenase activity. Involved in androgen biosynthetic process. Predicted to be located in cell body fiber; neuronal cell body; and perinuclear region of cytoplasm. Predicted to be active in endoplasmic reticulum membrane. Is expressed in alimentary system; genitourinary system; hypothalamus; and liver. Human ortholog(s) of this gene implicated in prostate cancer and prostatic hypertrophy. Orthologous to human SRD5A1 (steroid 5 alpha-reductase 1). PHENOTYPE: Female mice homozygous for a targeted mutation exhibit parturiton defects and deliver small litters. Male homozygous mice appear healthy. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
