Primary Identifier | MGI:1336892 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 22598 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables neutral L-amino acid:sodium:chloride symporter activity. Involved in neutral amino acid transport and renal amino acid absorption. Acts upstream of or within amino acid transmembrane transport. Located in apical plasma membrane and brush border membrane. Is expressed in several structures, including metanephros. Orthologous to human SLC6A18 (solute carrier family 6 member 18). PHENOTYPE: Homozygous null mice are overtly normal but have increased blood pressure associated with impaired renal accumulation of glycine. [provided by MGI curators] |