| Primary Identifier | MGI:1918414 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 71164 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-cysteine S-palmitoyltransferase activity. Involved in antiviral innate immune response; peptidyl-L-cysteine S-palmitoylation; and positive regulation of defense response to virus by host. Located in endosome membrane. Is expressed in brain; male reproductive gland or organ; metanephros; and submandibular gland. Orthologous to several human genes including ZDHHC11B (zinc finger DHHC-type containing 11B). PHENOTYPE: Mice homozygous for a null allele exhibit reduced circulating IL6 levels in response to LPS and D-galactosamine or HSV-1. Mice homozygous for a different null allele exhibit normal male fertility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
