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Protein Coding Gene : Slc9a3 solute carrier family 9 (sodium/hydrogen exchanger), member 3
Primary Identifier  MGI:105064 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  105243
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables PDZ domain binding activity and sodium:proton antiporter activity. Acts upstream of or within regulation of pH and sodium ion transport. Located in apical plasma membrane; brush border membrane; and vesicle. Is expressed in early conceptus; liver; metanephros; and oocyte. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 8. Orthologous to human SLC9A3 (solute carrier family 9 member A3).
PHENOTYPE: Homozygous mutant mice have diarrhea associated with defects of renal and intestinal absorption. Males are infertile. [provided by MGI curators]
  • synonyms:
  • AI930210,
  • NHE-3,
  • RIKEN cDNA 9030624O13 gene,
  • MGD-MRK-32103,
  • Slc9a3,
  • expressed sequence AI930210,
  • NHE3,
  • MGI:2145314,
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3,
  • 9030624O13Rik
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1 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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2 Driver For





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