Primary Identifier | MGI:1333776 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 11624 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable nuclear receptor activity and transcription cis-regulatory region binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of protein sumoylation. Located in nucleus. Is expressed in alimentary system; central nervous system; genitourinary system; spleen; and trachea. Orthologous to human AHRR (aryl hydrocarbon receptor repressor). PHENOTYPE: Mice homozygous for a null allele exhibit decreased susceptibility to chemically induced tumors. [provided by MGI curators] |