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Protein Coding Gene : Sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp)

Primary Identifier  MGI:1914195 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  66945
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable electron transfer activity; flavin adenine dinucleotide binding activity; and succinate dehydrogenase (quinone) activity. Predicted to contribute to succinate dehydrogenase activity. Predicted to be involved in mitochondrial electron transport, succinate to ubiquinone; nervous system development; and succinate metabolic process. Located in mitochondrial inner membrane and myelin sheath. Part of respiratory chain complex II (succinate dehydrogenase). Is active in mitochondrion. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and sensory organ. Human ortholog(s) of this gene implicated in Leigh disease; dilated cardiomyopathy 1GG; lung non-small cell carcinoma; mitochondrial complex II deficiency; and paraganglioma. Orthologous to human SDHA (succinate dehydrogenase complex flavoprotein subunit A).
  • synonyms:
  • expressed sequence C81073,
  • 2310034D06Rik,
  • RIKEN cDNA 2310034D06 gene,
  • MGI:2145519,
  • SDHF,
  • succinate dehydrogenase complex, subunit A, flavoprotein (Fp),
  • Sdha,
  • C81073,
  • SDH2,
  • FP

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For