| Primary Identifier | MGI:1924291 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 77041 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glucuronate-2-sulfatase activity. Predicted to be located in extracellular region and lysosome. Is expressed in aorta; genitourinary system; heart; and spinal cord. Used to study mucopolysaccharidosis. Human ortholog(s) of this gene implicated in mucopolysaccharidosis. Orthologous to human ARSK (arylsulfatase family member K). PHENOTYPE: Mice homozygous for a knock-out allele show moderate accumulation of heparan sulfate and chondroitin sulfate metabolites and signs of impaired social behavior and spatial reference memory in the absence of prominent lysosomal storage pathology. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
