| Primary Identifier | MGI:2679923 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 218343 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay and rescue of stalled ribosome. Predicted to be located in cytosol; euchromatin; and nucleoplasm. Predicted to be part of Ski complex. Human ortholog(s) of this gene implicated in trichohepatoenteric syndrome 1. Orthologous to human SKIC3 (SKI3 subunit of superkiller complex). PHENOTYPE: Mice homozygous for a knock-out allele show decreased embryo size, embryonic growth retardation, a small egg cylinder, disorganized extraembryonic tissue, and complete embryonic lethality by E9.5. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
