Primary Identifier | MGI:2145181 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 218441 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable 1-phosphatidylinositol binding activity and phosphatidylinositol-3,4,5-trisphosphate binding activity. Predicted to be involved in endosomal transport and protein targeting to lysosome. Predicted to be located in cytosol and early endosome. Predicted to be active in early endosome membrane. Is expressed in central nervous system and genitourinary system. Orthologous to human ZFYVE16 (zinc finger FYVE-type containing 16). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased common lymphocyte progenitor cell number in the bone marrow, increased T cell number in peripheral blood, and decreased B cell proliferation. [provided by MGI curators] |