Primary Identifier | MGI:2145236 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 218454 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in development of primary female sexual characteristics; development of primary male sexual characteristics; and positive regulation of fertilization. Predicted to be active in membrane. Is expressed in several structures, including central nervous system; hemolymphoid system gland; liver; reproductive system; and tail unsegmented mesenchyme. Orthologous to human LHFPL2 (LHFPL tetraspan subfamily member 2). PHENOTYPE: Females homozygous for a spontaneous point mutation have a completely closed vagina, soft swelling of the perineum and buildup of viscous fluid in the uteri. [provided by MGI curators] |