Primary Identifier | MGI:1349480 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 107767 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein domain specific binding activity. Acts upstream of or within establishment of localization in cell and exocytosis. Located in synaptic vesicle membrane and zymogen granule membrane. Is expressed in neural retinal epithelium; retina inner nuclear layer; retina nuclear layer; and retina outer nuclear layer. Orthologous to human SCAMP1 (secretory carrier membrane protein 1). PHENOTYPE: Mice homozygous for a targeted null mutation do not exhibit any overt abnormalities, but final cell capacitance of mast cells completing exocytosis was smaller than controls and an increased proportion of reversible fusion events was noted. [provided by MGI curators] |