Primary Identifier | MGI:2445123 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 218460 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in positive regulation of GTPase activity and regulation of autophagy. Located in cytoplasm. Orthologous to human WDR41 (WD repeat domain 41). PHENOTYPE: Mice homozygous for an ENU-generated allele exhibit increased susceptibility to DDS-induced colitis with increased activated single positive T cells. [provided by MGI curators] |