Primary Identifier | MGI:1919364 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 72114 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metal ion binding activity. Involved in several processes, including cytoskeleton organization; endoplasmic reticulum localization; and positive regulation of embryonic development. Acts upstream of or within negative regulation of protein phosphorylation; positive regulation of canonical Wnt signaling pathway; and protein stabilization. Located in cytosol and membrane. Is expressed in cerebral cortex ventricular layer; oocyte; ovary; and primary oocyte. Orthologous to human ZBED3 (zinc finger BED-type containing 3). PHENOTYPE: Homozygous knockout has a maternal effect in reduced litter size owing to cytoskeletal abnormalities affecting early zygote development. [provided by MGI curators] |