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Protein Coding Gene : Foxd1 forkhead box D1

Primary Identifier  MGI:1347463 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  15229
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including kidney development; luteinizing hormone secretion; and regulation of gene expression. Acts upstream of or within axon guidance and branching involved in ureteric bud morphogenesis. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; embryo mesenchyme; metanephros; nervous system; and sensory organ. Orthologous to human FOXD1 (forkhead box D1).
PHENOTYPE: Mice homozygous for this targeted mutation die within 24 hours after birth with severe defects in nephrogenesis, and abnormal development of the renal collecting system. [provided by MGI curators]
  • synonyms:
  • MGI:2145223,
  • expressed sequence AI385632,
  • forkhead box D1,
  • Foxd1,
  • Hfhbf2,
  • AI385632,
  • HNF-3/forkhead homolog, brain factor 2,
  • Hfh10,
  • MGI:99895,
  • MGD-MRK-16691,
  • FREAC4,
  • BF-2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

4 Driver For