| Primary Identifier | MGI:2178429 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 238803 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; nuclear estrogen receptor binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of intracellular estrogen receptor signaling pathway; negative regulation of transcription by RNA polymerase II; and response to estrogen. Located in nucleus. Used to study DiGeorge syndrome. Orthologous to human ZNF366 (zinc finger protein 366). PHENOTYPE: Mice homozygous for an ENU-induced mutation exhibit perimembranous and muscular ventricular septal defects (VSD), and overriding aorta. Short snout, micrognathia, micropthalmia, hypoplastic thymus, and hydronephrosis are also observed. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
