Primary Identifier | MGI:1298223 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 17940 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cysteine-type endopeptidase inhibitor activity involved in apoptotic process. Involved in negative regulation of apoptotic process and negative regulation of cysteine-type endopeptidase activity. Acts upstream of or within cellular response to estrogen stimulus and negative regulation of epithelial cell apoptotic process. Located in basolateral plasma membrane and cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and limb. Orthologous to human NAIP (NLR family apoptosis inhibitory protein). PHENOTYPE: Mice homozygous for disruptions in this gene display a normal phenotype. [provided by MGI curators] |