Primary Identifier | MGI:1918885 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 328329 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in cytoskeleton organization and intracellular signal transduction. Predicted to be located in cytoplasm. Is expressed in brain; thymus primordium; and ventral grey horn. Used to study Sertoli cell-only syndrome. Orthologous to human MAST4 (microtubule associated serine/threonine kinase family member 4). PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit abnormal incisor development, abnormal enamel maturation, malocclusion, amelogenesis imperfecta, and male infertility with male germ cell depletion. [provided by MGI curators] |