Primary Identifier | MGI:3608341 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 238875 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within B cell homeostasis and B cell proliferation involved in immune response. Predicted to be located in Golgi apparatus and plasma membrane. Orthologous to human GAPT (GRB2 binding adaptor protein, transmembrane). PHENOTYPE: Mice homozygous for a null allele exhibit increased B cell proliferation, marginal zone B cell numbers and concentrations of IgM, IgG2b and IgG3. [provided by MGI curators] |