| Primary Identifier | MGI:2145534 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 218630 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in G1/S transition of mitotic cell cycle; cilium assembly; and multi-ciliated epithelial cell differentiation. Located in cytoplasm. Is expressed in brain; nasal epithelium; reproductive system; and trachea. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 29. Orthologous to human CCNO (cyclin O). PHENOTYPE: Mice homozygous for a knock-out allele exhibit pre-weaning lethality after E17, hydrocephaly, growth retardation, enlarged brain ventricles, thin cerebral cortex, nasal cavity congestion and impaired formation of deuterosomes and centrioles. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
