Primary Identifier | MGI:1298232 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 14945 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable serine-type endopeptidase activity. Predicted to be involved in granzyme-mediated programmed cell death signaling pathway and protein maturation. Predicted to be active in extracellular space. Is expressed in several structures, including eye; forebrain; lung; small intestine; and spleen. Orthologous to human GZMK (granzyme K). PHENOTYPE: Mice homozygous for a knock-out allele are healthy, anatomically normal, fertile and show normal hematopoietic development and normal recovery from lymphocytic choriomeningitis virus and Ectromelia virus infection. [provided by MGI curators] |