| Primary Identifier | MGI:1861731 | Organism | mouse, laboratory |
| Chromosome | 13 | NCBI Gene Number | 56838 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chemokine activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide; cell chemotaxis; and killing of cells of another organism. Acts upstream of or within positive regulation of cytosolic calcium ion concentration. Predicted to be active in extracellular space. Predicted to colocalize with secretory granule. Orthologous to human CCL28 (C-C motif chemokine ligand 28). PHENOTYPE: Mice homozygous for a null allele exhibit a reduction and abnormal distribution of IgA antibody-secreting cells, decreased IgA secretion, increase in Class Bacilli in the gut, and increased susceptibility to induced colitis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
