Primary Identifier | MGI:1913481 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 66231 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in cytosol and nuclear speck. Predicted to be part of THO complex part of transcription export complex. Predicted to colocalize with chromosome, telomeric region. Is expressed in inferior colliculus; midbrain ventricular layer; submandibular gland primordium; telencephalon ventricular layer; and vibrissa. Orthologous to human THOC7 (THO complex subunit 7). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality between implantation and somite formation. In vitro outgrowth assays show that blastocysts hatch from the zona pellucida but form irregular outgrowths. [provided by MGI curators] |