Primary Identifier | MGI:1298229 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 18074 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity. Predicted to be an extracellular matrix structural constituent. Acts upstream of or within cell-matrix adhesion. Located in basement membrane. Is expressed in several structures, including alimentary system; extraembryonic component; genitourinary system; musculature; and nervous system. Orthologous to human NID2 (nidogen 2). PHENOTYPE: Mice homozygous for a null alleleexhibit calcification of joint cartilage and osteoarthritis. [provided by MGI curators] |