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Protein Coding Gene : Cacna2d3 calcium channel, voltage-dependent, alpha2/delta subunit 3
Primary Identifier  MGI:1338890 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  12294
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable voltage-gated calcium channel activity. Involved in regulation of presynapse organization. Is active in GABA-ergic synapse and presynaptic active zone membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and immune system. Orthologous to human CACNA2D3 (calcium voltage-gated channel auxiliary subunit alpha2delta 3).
PHENOTYPE: Mice homozygous for disruptions in this gene have a decreased startle reflex and occasional animals show increased aggression and hyperactivity. [provided by MGI curators]
  • synonyms:
  • Cacna2d3,
  • calcium channel, voltage-dependent, alpha2/delta subunit 3,
  • alpha2delta3,
  • alpha 2 delta-3
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