Primary Identifier | MGI:1923151 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 75901 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; kinesin binding activity; and mRNA binding activity. Predicted to be involved in deadenylation-dependent decapping of nuclear-transcribed mRNA; deadenylation-independent decapping of nuclear-transcribed mRNA; and protein localization to cytoplasmic stress granule. Predicted to act upstream of or within positive regulation of DNA-templated transcription and transforming growth factor beta receptor signaling pathway. Located in P-body. Is expressed in several structures, including genitourinary system; limb; liver; muscle tissue; and spleen. Orthologous to human DCP1A (decapping mRNA 1A). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic growth retardation and die around E10.5. [provided by MGI curators] |