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Protein Coding Gene : Mettl6 methyltransferase 6, methylcytidine
Primary Identifier  MGI:1914261 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  67011
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables tRNA (cytidine-3-)-methyltransferase activity. Involved in tRNA methylation. Predicted to be located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; respiratory system; sensory organ; and urinary system. Orthologous to human METTL6 (methyltransferase 6, tRNA N3-cytidine).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced 3-methylcytidine (m3C) methyltransferases modification of tRNA. [provided by MGI curators]
  • synonyms:
  • 1600013P15Rik,
  • expressed sequence AI467521,
  • AI467521,
  • AU020711,
  • MGI:2145737,
  • Mettl6,
  • MGI:2145663,
  • RIKEN cDNA 1600013P15 gene,
  • methyltransferase 6, methylcytidine,
  • expressed sequence AU020711
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