| Primary Identifier | MGI:1921677 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 74427 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription elongation factor activity. Predicted to be involved in regulation of transcription elongation by RNA polymerase II and transcription elongation by RNA polymerase II. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in intercellular bridge and nuclear body. Predicted to be part of transcription elongation factor complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human EAF1 (ELL associated factor 1). PHENOTYPE: Homozygous knockout is embryonic lethal. Conditional homozygous KO in prostate epithelium leads to prostate inflammation and an increased prostatic intraepithelial neoplasia incidence. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
