Primary Identifier | MGI:1858317 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 53600 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable enzyme binding activity and protein transmembrane transporter activity. Predicted to be involved in positive regulation of protein processing; protein transport; and type 2 mitophagy. Located in migrasome and mitochondrion. Is expressed in several structures, including central nervous system; heart; orbito-sphenoid; submandibular gland primordium; and tooth. Orthologous to several human genes including TIMM23 (translocase of inner mitochondrial membrane 23). PHENOTYPE: Mice homozygous for a gene trapped allele die prior to E3.5. Mice heterogygous for this allele exhibit background sensitive premature aging and increased mortality. [provided by MGI curators] |