Primary Identifier | MGI:3584510 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 545030 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within with a positive effect on CD8-positive, alpha-beta T cell activation. Acts upstream of or within antigen processing and presentation and cellular response to virus. Predicted to be located in early endosome and endoplasmic reticulum. Orthologous to human WDFY4 (WDFY family member 4). PHENOTYPE: Mice homozygous for a null allele exhibit reduced CD103+ CD11bneg migratory cDC1 cells in the mesenteric lymph nodes and failure to reject 1969 sarcoma cells. [provided by MGI curators] |