Primary Identifier | MGI:1196295 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 19256 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable histone H2AXY142 phosphatase activity; non-membrane spanning protein tyrosine phosphatase activity; and protein tyrosine phosphatase activity, metal-dependent. Predicted to be involved in lymphangiogenesis. Predicted to be located in centriolar satellite. Predicted to be active in cytoplasm. Is expressed in epididymis; metanephros; submandibular gland; and testis. Orthologous to human PTPN20 (protein tyrosine phosphatase non-receptor type 20). PHENOTYPE: Mice homozygous for a null allele exhibit non-obstructive hydrocephaly and enlarged brain ventricles due to disrupted CSF drainage. [provided by MGI curators] |