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Protein Coding Gene : Ptpn20 protein tyrosine phosphatase, non-receptor type 20

Primary Identifier  MGI:1196295 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  19256
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable histone H2AXY142 phosphatase activity; non-membrane spanning protein tyrosine phosphatase activity; and protein tyrosine phosphatase activity, metal-dependent. Predicted to be involved in lymphangiogenesis. Predicted to be located in centriolar satellite. Predicted to be active in cytoplasm. Is expressed in epididymis; metanephros; submandibular gland; and testis. Orthologous to human PTPN20 (protein tyrosine phosphatase non-receptor type 20).
PHENOTYPE: Mice homozygous for a null allele exhibit non-obstructive hydrocephaly and enlarged brain ventricles due to disrupted CSF drainage. [provided by MGI curators]
  • synonyms:
  • protein tyrosine phosphatase, non-receptor type 20,
  • typ,
  • Ptpn20

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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