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Protein Coding Gene : Rbp3 retinol binding protein 3, interstitial
Primary Identifier  MGI:97878 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  19661
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable retinol binding activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular space and interphotoreceptor matrix. Predicted to be active in cone matrix sheath. Is expressed in eye; retina; retina nuclear layer; and retina outer nuclear layer. Human ortholog(s) of this gene implicated in retinitis pigmentosa 66. Orthologous to human RBP3 (retinol binding protein 3).
PHENOTYPE: Mice homozygous for disruptions in this gene experience photoreceptor degeneration. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-13789,
  • MGD-MRK-11462,
  • interphotoreceptor retinoid-binding prot,
  • Irbp,
  • Rbp3,
  • retinol binding protein 3, interstitial,
  • MGD-MRK-13794,
  • Rbp-3
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Disease

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