Primary Identifier | MGI:1298397 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 20618 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable alpha-tubulin binding activity; beta-tubulin binding activity; and cuprous ion binding activity. Involved in protein secretion. Acts upstream of or within several processes, including adult locomotory behavior; chemical synaptic transmission; and regulation of secretion by cell. Located in axon; cytoplasm; and neuronal cell body. Is expressed in several structures, including adipose tissue; alimentary system; central nervous system; eye; and hemolymphoid system gland. Used to study amyotrophic lateral sclerosis type 1. Human ortholog(s) of this gene implicated in Lewy body dementia. Orthologous to human SNCG (synuclein gamma). PHENOTYPE: Homozygous null mice are viable, fertile, and show no morphological or functional abnormalities of the nervous system. [provided by MGI curators] |