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Protein Coding Gene : Sncg synuclein, gamma

Primary Identifier  MGI:1298397 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  20618
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable alpha-tubulin binding activity; beta-tubulin binding activity; and cuprous ion binding activity. Involved in protein secretion. Acts upstream of or within several processes, including adult locomotory behavior; chemical synaptic transmission; and regulation of secretion by cell. Located in axon; cytoplasm; and neuronal cell body. Is expressed in several structures, including adipose tissue; alimentary system; central nervous system; eye; and hemolymphoid system gland. Used to study amyotrophic lateral sclerosis type 1. Human ortholog(s) of this gene implicated in Lewy body dementia. Orthologous to human SNCG (synuclein gamma).
PHENOTYPE: Homozygous null mice are viable, fertile, and show no morphological or functional abnormalities of the nervous system. [provided by MGI curators]
  • synonyms:
  • synuclein, gamma,
  • MGI:1353613,
  • persyn,
  • C79089,
  • Sncg,
  • EST C79089

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For