| Primary Identifier | MGI:2385618 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 105450 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable receptor ligand activity. Predicted to be an extracellular matrix structural constituent. Involved in cell migration involved in sprouting angiogenesis; negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis; and positive regulation of defense response to bacterium. Located in basement membrane. Is expressed in several structures, including cardiovascular system; early conceptus; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human MMRN2 (multimerin 2). PHENOTYPE: Mice homozygous for a null allele display abnormal blood vessel morphology, vascular leakage, and increased density of small vessels in tumors. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
