Primary Identifier | MGI:2675859 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 218914 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP-dependent protein-DNA unloader activity. Predicted to be involved in several processes, including mitotic sister chromatid segregation; negative regulation of DNA replication; and negative regulation of sister chromatid cohesion. Predicted to be located in several cellular components, including intercellular bridge; mitotic spindle; and nucleoplasm. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and respiratory system. Orthologous to human WAPL (WAPL cohesin release factor). PHENOTYPE: Mice homozygous for a targeted allele exhibit prenatal lethality. [provided by MGI curators] |