Primary Identifier | MGI:1858963 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 54342 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables glucosamine 6-phosphate N-acetyltransferase activity. Involved in UDP-N-acetylglucosamine biosynthetic process. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in Golgi apparatus; endoplasmic reticulum-Golgi intermediate compartment; and late endosome. Is expressed in several structures, including alimentary system; brain; integumental system; respiratory system; and sensory organ. Orthologous to human GNPNAT1 (glucosamine-phosphate N-acetyltransferase 1). PHENOTYPE: Mutation of this gene result in homozygous lethality by E7.5 with various developmental defects observed. [provided by MGI curators] |