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Protein Coding Gene : Fermt2 fermitin family member 2
Primary Identifier  MGI:2385001 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  218952
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables actin filament binding activity. Involved in several processes, including focal adhesion assembly; integrin activation; and positive regulation of osteoblast differentiation. Located in stress fiber. Is expressed in several structures, including brain; genitourinary system; gut; immune system; and musculature. Orthologous to human FERMT2 (FERM domain containing kindlin 2).
PHENOTYPE: Homozygous mice are embryonic lethal at or before E7.5. [provided by MGI curators]
  • synonyms:
  • Mig2,
  • AA960555,
  • Kindlin-2,
  • Plekhc1,
  • Fermt2,
  • MGI:2145587,
  • expressed sequence AA960555,
  • fermitin family member 2,
  • pleckstrin homology domain containing, family C (with FERM domain) member 1
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

9 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For





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