| Primary Identifier | MGI:2145645 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 105504 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable small GTPase binding activity. Involved in protein localization to plasma membrane. Acts upstream of or within with a positive effect on establishment of planar polarity. Acts upstream of or within with a negative effect on epithelial cell apoptotic process. Acts upstream of or within non-motile cilium assembly. Predicted to be located in cytosol. Predicted to be part of exocyst. Is expressed in 1-cell stage embryo; cerebral cortex ventricular layer; cortical plate; primary oocyte; and secondary oocyte. Used to study obstructive nephropathy. Orthologous to human EXOC5 (exocyst complex component 5). PHENOTYPE: Mice homozygous for a conditional allele activated in all cells die prior to E8.5. Mice homozygous for a conditional allele activated in kidney cells exhibit ureteropelvic junction obstructions leading to neontal death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
