Primary Identifier | MGI:2685134 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 239083 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Involved in chiasma assembly. Acts upstream of or within blastocyst formation and spermatid development. Located in condensed nuclear chromosome. Colocalizes with synaptonemal complex. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human CCNB1IP1 (cyclin B1 interacting protein 1). PHENOTYPE: Mice homozygous for an ENU-induced mutation have abnormal testicular and ovarian morphology and exhibit sterility in both sexes owing to meiotic defects. [provided by MGI curators] |