Primary Identifier | MGI:2448501 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 219024 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity. Involved in positive regulation of TORC1 signaling and proton-transporting V-type ATPase complex assembly. Located in bounding membrane of organelle and plasma membrane. Orthologous to human PIP4P1 (phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete embryonic lethality associated with embryonic growth arrest at E9.5. [provided by MGI curators] |