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Protein Coding Gene : Rnase4 ribonuclease, RNase A family 4
Primary Identifier  MGI:1926217 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  58809
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable RNA nuclease activity. Involved in antibacterial humoral response. Acts upstream of or within cellular response to starvation. Located in extracellular space. Is expressed in alimentary system; embryo mesenchyme; and urinary system. Orthologous to human RNASE4 (ribonuclease A family member 4).
PHENOTYPE: Homozygous null mice show increased susceptibility to induced colitis with altered intestinal microbiota. [provided by MGI curators]
  • synonyms:
  • ribonuclease, RNase A family 4,
  • Rnase4,
  • RIKEN cDNA C730049F20 gene,
  • C730049F20Rik,
  • MGI:2442584
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1 Involved In Mutations

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