Primary Identifier | MGI:2155260 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 140743 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTP binding activity; GTPase activity; and calcium channel regulator activity. Predicted to be active in plasma membrane. Is expressed in central nervous system; epithelium; and limb. Orthologous to human REM2 (RRAD and GEM like GTPase 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit strain-specific impaired viability and fertility as well as altered intrinsic excitability and spontaneous firing in visual circuits. [provided by MGI curators] |