| Primary Identifier | MGI:1351645 | Organism | mouse, laboratory |
| Chromosome | 14 | NCBI Gene Number | 27374 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including E-box binding activity; protein-arginine N-methyltransferase activity; and transcription corepressor activity. Involved in circadian regulation of gene expression and gene expression. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in cytoplasm and male germ cell nucleus. Part of histone methyltransferase complex. Is expressed in several structures, including blastocyst; early embryo; oocyte; retina nuclear layer; and telencephalon. Used to study idiopathic scoliosis. Orthologous to human PRMT5 (protein arginine methyltransferase 5). PHENOTYPE: Mice homozygous for a null allele display embryonic lethality before somite formation with failure of inner cell mass proliferation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
