Primary Identifier | MGI:2155888 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 140806 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cytokine activity. Acts upstream of or within several processes, including eosinophil differentiation; positive regulation of transcription by RNA polymerase II; and response to nematode. Predicted to be located in extracellular space. Orthologous to human IL25 (interleukin 25). PHENOTYPE: Mice homozygous for a null allele have increased susceptibility to parasitic infection. Male homozygous mutant mice exhibit notably increased mean serum triglyceride levels in another null allele. [provided by MGI curators] |