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Protein Coding Gene : Dhrs4 dehydrogenase/reductase 4
Primary Identifier  MGI:90169 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  28200
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables retinal dehydrogenase activity. Acts upstream of or within retinal metabolic process. Located in mitochondrion and peroxisome. Orthologous to several human genes including DHRS4 (dehydrogenase/reductase 4).
PHENOTYPE: Homozygous mutant mice exhibit a decreased mean serum IgG2a response to ovalbumin challenge when compared with that of controls. Female mutants exhibit an increased depressive-like response during tail suspension testing. [provided by MGI curators]
  • synonyms:
  • RRD,
  • dehydrogenase/reductase (SDR family) member 4,
  • expressed sequence AI043103,
  • DNA segment, Chr 14, University of California at Los Angeles 2,
  • D14Ucla2,
  • dehydrogenase/reductase 4,
  • AI790593,
  • MGI:2145595,
  • Dhrs4,
  • AI043103,
  • MGI:2145693,
  • MGD-MRK-3967,
  • expressed sequence AI790593
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Features --> Cross References

Genome

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1 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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