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Protein Coding Gene : Cpne6 copine VI
Primary Identifier  MGI:1334445 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  12891
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables phosphatidylserine binding activity. Involved in cellular response to calcium ion and postsynaptic actin cytoskeleton organization. Located in several cellular components, including axon; clathrin-coated endocytic vesicle; and dendrite. Is expressed in brain; future brain; and hippocampus. Orthologous to human CPNE6 (copine 6).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired synaptic plasticity, reduced long term potentiation, and deficits in hippocampus-dependent learning and memory. [provided by MGI curators]
  • synonyms:
  • MGI:2145848,
  • expressed sequence BB076446,
  • BB076446,
  • neuronal copine,
  • copine VI,
  • expressed sequence AU067659,
  • Cpne6,
  • AU067659,
  • MGI:2145764
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Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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2 Driver For





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