Primary Identifier | MGI:1915930 | Organism | mouse, laboratory |
Chromosome | 14 | NCBI Gene Number | 68680 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables diacylglycerol binding activity and triglyceride binding activity. Involved in lipid droplet formation and positive regulation of sequestering of triglyceride. Located in endoplasmic reticulum membrane. Is expressed in genitourinary system; gut; liver; lung; and musculature. Orthologous to human FITM1 (fat storage inducing transmembrane protein 1). PHENOTYPE: Homozygous knockout increases survival after pressure overload-induced heart failure. [provided by MGI curators] |